Tuberculosis
World TB Day: U.S. Cases Hit New Low, Integration with HIV Care Needed Worldwide
- Details
- Category: Tuberculosis (TB)
- Published on Sunday, 24 March 2013 00:00
- Written by Liz Highleyman
The number of new tuberculosis (TB) cases in the U.S. fell below 10,000 in 2012 -- the lowest rate since tallying began in the early 1950s, according to a Centers for Disease Control and Prevention(CDC) report released ahead of World TB Day on March 24. But the news is not all good, as novel treatments and better integration of care are needed on a global basis.
CROI 2013: Researchers Discuss Advances in Tuberculosis Treatment
- Details
- Category: Tuberculosis (TB)
- Published on Monday, 11 March 2013 00:00
- Written by Keith Alcorn
A new two-drug combination of rifapentine and moxifloxacin can allow tuberculosis (TB) treatment to be taken just once-weekly during the 4-month continuation phase, according to a presentation at the 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) last week in Atlanta. A related meta-analysis found that rifampicin, a key drug in TB treatment, can be tolerated at much higher levels than used in current clinical practice, suggesting that higher doses might allow the treatment course to be shortened.
Bedaquiline Approved for Multidrug-resistant Tuberculosis after Long Wait
- Details
- Category: Tuberculosis (TB)
- Published on Thursday, 03 January 2013 00:00
- Written by Liz Highleyman
The U.S. Food and Drug Administration last week approved bedaquiline (brand name Sirturo, formerly TMC207) as part of a combination regimen for adults with multidrug-resistant pulmonary tuberculosis (TB) -- the first approval of a new TB drug in more than 40 years.
Experimental MVA Tuberculosis Vaccine Fails to Protect Infants
- Details
- Category: Tuberculosis (TB)
- Published on Tuesday, 12 February 2013 00:00
- Written by Liz Highleyman
An investigational tuberculosis (TB) vaccine did not provide significant additional protection for babies who were previously immunized with the partially effective standard BCG vaccine, though it did stimulate immune response, researchers reported in the February 4, 2013, advance online edition of The Lancet.
FDA Committee Supports Accelerated Approval of TB Drug Bedaquiline
- Details
- Category: Tuberculosis (TB)
- Published on Friday, 30 November 2012 00:00
- Written by Liz Highleyman
The U.S. Food and Drug Administration (FDA) Anti-Infective Drugs Advisory Committee this week gave a favorable opinion on Janssen's request for accelerated approval of its investigational tuberculosis drug bedaquiline (also known as Sirturo, formerly TMC207) for treatment of multidrug-resistance TB (MDR-TB).
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